In case your family members have not got adjacent seats during automatic seat assignment then make a humble request to other travellers and try for seat exchange so that all of you can sit together.
Keep good collection of your favourite songs in your cell phone or mp3 player. Also do not forget to carry your earphone with you.
In case you want to take a longer break at some bus stop due to natures call then inform the bus conductor about the delay so that he will wait for you.