Bus journey gets more comfortable in large groups because you spend your time in talking to your known ones. Hence if possible try to get people along with you during bus journey.
When your destination is about to arrive, just be ready with your bags and count all the items. Most of the people do this mistake and they often miss their belongings in the bus.
In case you want to take a longer break at some bus stop due to natures call then inform the bus conductor about the delay so that he will wait for you.